Scott Valentine

Pinky and Brain are genetically enhanced laboratory mice who reside in a cage in the Acme Labs research facility. Brain is self-centered and scheming; Pinky is good-natured but feebleminded. In each episode, Brain devises a new plan to take over the world, which ultimately ends in failure, usually due to Pinky's idiocy, the impossibility of Brain's plan, Brain's own arrogance, or just circumstances beyond their control.

Former 1960s flower children Steven and Elyse Keaton raise their conservative son Alex, daughters Mallory and Jennifer, and later, youngest child Andrew.